Inhibition of Mitochondrial Uncoupling Proteins Arrests Human Spermatozoa Motility without Compromising Viability

• Main Authors: David F. Carrageta (Author), Laís Freire-Brito (Author), Bárbara Guerra-Carvalho (Author), João C. Ribeiro (Author), Bruno S. Monteiro (Author), Alberto Barros (Author), Pedro F. Oliveira (Author), Mariana P. Monteiro (Author), Marco G. Alves (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mitochondrial uncoupling proteins (UCPs) are central in the regulation of mitochondrial activity and reactive oxygen species (ROS) production. High oxidative stress is a major cause of male infertility; however, UCPs expression and function in human spermatozoa are still unknown. Herein, we aimed to...