New Chloramphenicol Derivatives with a Modified Dichloroacetyl Tail as Potential Antimicrobial Agents

• Main Authors: Artemis Tsirogianni (Author), Georgia G. Kournoutou (Author), Anthony Bougas (Author), Eleni Poulou-Sidiropoulou (Author), George Dinos (Author), Constantinos M. Athanassopoulos (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To combat the dangerously increasing pathogenic resistance to antibiotics, we developed new pharmacophores by chemically modifying a known antibiotic, which remains to this day the most familiar and productive way for novel antibiotic development. We used as a starting material the chloramphenicol b...