Solid Dispersions of Genistein via Solvent Rotary Evaporation for Improving Solubility, Bioavailability, and Amelioration Effect in HFD-Induced Obesity Mice

• Hoofdauteurs: Chenxu Qiu (Auteur), Yancui Zhang (Auteur), Yingsai Fan (Auteur), Shupeng Li (Auteur), Jianting Gao (Auteur), Xin He (Auteur), Xinghua Zhao (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2024-02-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Genistein (GEN) is an active pharmaceutical ingredient that presents the challenges of poor water solubility and low oral bioavailability. To tackle these challenges, a GEN solid dispersion was prepared by solvent rotary evaporation using polyvinylpyrrolidone K30 (PVP K30) as a carrier. The optimal...