Inducible transgene expression in PDX models in vivo identifies KLF4 as a therapeutic target for B-ALL

Inducible transgene expression in PDX models in vivo identifies KLF4 as a therapeutic target for B-ALL

Abstract Background Clinically relevant methods are not available that prioritize and validate potential therapeutic targets for individual tumors, from the vast amount of tumor descriptive expression data. Methods We established inducible transgene expression in clinically relevant patient-derived...

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Main Authors: Wen-Hsin Liu (Author), Paulina Mrozek-Gorska (Author), Anna-Katharina Wirth (Author), Tobias Herold (Author), Larissa Schwarzkopf (Author), Dagmar Pich (Author), Kerstin Völse (Author), M. Camila Melo-Narváez (Author), Michela Carlet (Author), Wolfgang Hammerschmidt (Author), Irmela Jeremias (Author)
Format: Book
Published: BMC, 2020-09-01T00:00:00Z.
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