Simulation-Based Engineering of Humanized Scfv Antibody against hTNF-α

• Auteurs principaux: Maryam Hamzeh-Mivehroud (Auteur), Ayda Baghal Safarizad (Auteur), Siavoush Dastmalchi (Auteur)
• Format: Livre
• Publié: Tabriz University of Medical Sciences, 2020-03-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Background: Uncontrolled activity of tumor necrosis factor alpha (TNF-α) as pro-inflammatory cytokine has been linked with pathogenesis of autoimmune/inflammatory diseases. Therefore, modulating of TNF-α associated biological pathways is a promising strategy for alleviating of such diseases. In view...