Killing a fly with a sledgehammer: Atezolizumab exposure in real‐world lung cancer patients

• Main Authors: Sophie Marolleau (Author), Alice Mogenet (Author), Clara Boeri (Author), Mourad Hamimed (Author), Joseph Ciccolini (Author), Laurent Greillier (Author)
• Format: Book
• Published: Wiley, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Atezolizumab is an anti‐PDL1 approved for treating lung cancer. A threshold of 6 μg/mL in plasma has been associated with target engagement. The extent to which patients could be overexposed with the standard 1200 mg q3w dosing remains unknown. Here, we monitored atezolizumab peak and troug...