Protective role of crocin against sepsis-induced injury in the liver, kidney and lungs via inhibition of p38 MAPK/NF-κB and Bax/Bcl-2 signalling pathways

• Автори: Jun Gao (Автор), Feng Zhao (Автор), Shaona Yi (Автор), Shuhang Li (Автор), Aiqing Zhu (Автор), Yingxiu Tang (Автор), Aiqun Li (Автор)
• Формат: Книга
• Опубліковано: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Context Crocin has been reported to have multiple bioactivities. However, the effect of crocin administration on caecal ligation and puncture (CLP)-induced sepsis remains unknown.Objective We investigated the effects of crocin on CLP-induced sepsis in mice and the underlying mechanism of action.Mate...