Enhancement of Skin Permeability Prediction through PBPK Modeling, Bayesian Inference, and Experiment Design

Physiologically based pharmacokinetic (PBPK) models of skin absorption are a powerful resource for estimating drug delivery and chemical risk of dermatological products. This paper presents a PBPK workflow for the quantification of the mechanistic determinants of skin permeability and the use of the...

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Autores principales: Abdullah Hamadeh (Autor), Abdulkarim Najjar (Autor), John Troutman (Autor), Andrea Edginton (Autor)
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Publicado: MDPI AG, 2023-11-01T00:00:00Z.
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