More robust gut immune responses induced by combining intranasal and sublingual routes for prime-boost immunization

• Main Authors: Hye Suk Hwang (Author), Sao Puth (Author), Wenzhi Tan (Author), Vivek Verma (Author), Kwangjoon Jeong (Author), Shee Eun Lee (Author), Joon Haeng Rhee (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Norovirus causes acute and debilitating gastroenteritis, characterized by vomiting and diarrhea. We recently reported a recombinant GII. 4 P domain particle (Pd) vaccine adjuvanted with a flagellin, Vibrio vulnificus FlaB, effectively promoting both humoral and cell-mediated immune responses. In the...