Expression of the Metalloproteinase ADAM8 Is Upregulated in Liver Inflammation Models and Enhances Cytokine Release In Vitro

• Главные авторы: Tanzeela Awan (Автор), Aaron Babendreyer (Автор), Justyna Wozniak (Автор), Abid Mahmood Alvi (Автор), Viktor Sterzer (Автор), Lena Cook (Автор), Jörg W. Bartsch (Автор), Christian Liedtke (Автор), Daniela Yildiz (Автор), Andreas Ludwig (Автор)
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• Опубликовано: Hindawi Limited, 2021-01-01T00:00:00Z.
• Предметы: article
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Acute and chronic liver inflammation is driven by cytokine and chemokine release from various cell types in the liver. Here, we report that the induction of inflammatory mediators is associated with a yet undescribed upregulation of the metalloproteinase ADAM8 in different murine hepatitis models. W...