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Development of novel ultra-sensitive IL-11 target engagement assays to support mechanistic PK/PD modeling for an anti-IL-11 antibody therapeutic

An in-house antibody generation campaign identified a diverse, high affinity set of anti-interleukin-11 (IL-11) monoclonal antibodies (mAbs) to enable successful development of novel, custom ultra-sensitive target engagement assays for detection of "free" (unbound to the dosed anti-IL-11 t...

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Bibliographic Details
Main Authors:	Maria Myzithras (Author), Siqi Lin (Author), Legairre Radden (Author), Cynthia Hess Kenny (Author), Zheng Cai (Author), Angus MacDonald (Author), Ralph Binetti (Author), Michael Marlow (Author), Paul Fracasso (Author), Glenn Gibson (Author), Christina Bartlett (Author), Julie Hawkins (Author), Steven Hansel (Author)
Format:	Book
Published:	Taylor & Francis Group, 2022-12-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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