Hepatic follistatin increases basal metabolic rate and attenuates diet-induced obesity during hepatic insulin resistance

• Egile Nagusiak: Rongya Tao (Egilea), Oliver Stöhr (Egilea), Caixia Wang (Egilea), Wei Qiu (Egilea), Kyle D. Copps (Egilea), Morris F. White (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2023-05-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Objective: Body weight change and obesity follow the variance of excess energy input balanced against tightly controlled EE (energy expenditure). Since insulin resistance can reduce energy storage, we investigated whether genetic disruption of hepatic insulin signaling reduced adipose mass with incr...