Population pharmacokinetics of benznidazole in neonates, infants and children using a new pediatric formulation.

• Main Authors: Jaime Altcheh (Author), Guillermo Moscatelli (Author), Martin Caruso (Author), Samanta Moroni (Author), Margarita Bisio (Author), Maria Rosa Miranda (Author), Celia Monla (Author), Maria Vaina (Author), Maria Valdez (Author), Lucrecia Moran (Author), Teresa Ramirez (Author), Oscar Ledesma Patiño (Author), Adelina Riarte (Author), Nicolas Gonzalez (Author), Jayme Fernandes (Author), Fabiana Alves (Author), Isabela Ribeiro (Author), Facundo Garcia-Bournissen (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>There is a major need for information on pharmacokinetics (PK) of benznidazole (BNZ) in children with Chagas disease (CD). We conducted a multicentre population PK, safety and efficacy study in children, infants and neonates with CD treated with BNZ (formulated in 100...