Matrine Promotes Human Myeloid Leukemia Cells Apoptosis Through Warburg Effect Mediated by Hexokinase 2

• Main Authors: Guibin Lin (Author), Yangzhe Wu (Author), Fengtao Cai (Author), Zhen Li (Author), Shixin Su (Author), Jian Wang (Author), Jialin Cao (Author), Lingdi Ma (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Matrine, an alkaloid compound isolated from the medicinal plant Sophora flavescens, inhibits many types of cancer proliferation. However, the precise mechanism of the matrine antihuman chronic myeloid leukemia remains unclear. In this study, we showed that matrine significantly inhibited the cell pr...