NEMO-Binding Domain Peptide Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting the NF-κB Signaling Pathway

• Autores principales: Jianhua Huang (Autor), Li Li (Autor), Weifeng Yuan (Autor), Linxin Zheng (Autor), Zhenhui Guo (Autor), Wenjie Huang (Autor)
• Formato: Libro
• Publicado: Hindawi Limited, 2016-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

The aim of the present study is to investigate the protective effects and relevant mechanisms exerted by NEMO-binding domain peptide (NBD) against lipopolysaccharide- (LPS-) induced acute lung injury (ALI) in mice. The ALI model was induced by intratracheally administered atomized LPS (5 mg/kg) to B...