Antioxidant and Anticancer Functions of Protein Acyltransferase DHHC3

• Main Authors: Chandan Sharma (Author), Martin E. Hemler (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2022-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Silencing of DHHC3, an acyltransferase enzyme in the DHHC family, extensively upregulates oxidative stress (OS). Substrates for DHHC3-mediated palmitoylation include several antioxidant proteins and many other redox regulatory proteins. This helps to explain why DHHC3 ablation upregulates OS. DHHC3...