Lcz696 Alleviates Myocardial Fibrosis After Myocardial Infarction Through the sFRP-1/Wnt/β-Catenin Signaling Pathway

Background: Lcz696 (ARNI, angiotensin receptor-neprilysin inhibitor; sacubitril/valsartan) shows an inhibitory effect on fibrosis after myocardial infarction (MI). However, the underlying signaling mechanisms are poorly understood. The Wnt/β-catenin signaling pathway is activated after MI and partic...

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Main Authors: Jing Liu (Author), Xuehui Zheng (Author), Chen Zhang (Author), Chunmei Zhang (Author), Peili Bu (Author)
Format: Book
Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
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