To Enhance Mucus Penetration and Lung Absorption of Drug by Inhalable Nanocrystals-In-Microparticles

• Главные авторы: Guiting Huang (Автор), Shuyuan Shuai (Автор), Weicheng Zhou (Автор), Yingchong Chen (Автор), Baode Shen (Автор), Pengfei Yue (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2022-02-01T00:00:00Z.
• Предметы: article
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To effectively achieve the pulmonary delivery for curcumin (CN), novel inhalable mucus-penetrating nanocrystal-based microparticles (INMP) were designed. The D-Tocopherol acid polyethylene glycol 1000 succinate (TPGS) modified CN nanocrystals (CN-NS@TPGS) were prepared by high pressure homogenizatio...