Delivery of antisense oligonucleotide using polyethylenimine-based lipid nanoparticle modified with cell penetrating peptide

Efficient and stable delivery system of antisense oligonucleotide (ASO) is important and urgently needed. Here, an ASO delivery system, Lp-PPRP, which contains a cationic polymer based on PEI (branched, 25 kDa), named PEI-PC and a palmitic acid modified R8 (R8-PA) was prepared to deliver a kind of A...

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Hoofdauteurs: Shuang Yang (Auteur), Dandan Wang (Auteur), Yaojun Sun (Auteur), Bin Zheng (Auteur)
Formaat: Boek
Gepubliceerd in: Taylor & Francis Group, 2019-01-01T00:00:00Z.
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