Procognitive, Anxiolytic, and Antidepressant-like Properties of Hyperoside and Protocatechuic Acid Corresponding with the Increase in Serum Serotonin Level after Prolonged Treatment in Mice

• Main Authors: Jolanta Orzelska-Górka (Author), Katarzyna Dos Santos Szewczyk (Author), Monika Gawrońska-Grzywacz (Author), Mariola Herbet (Author), Anna Lesniak (Author), Anna Bielenica (Author), Magdalena Bujalska-Zadrożny (Author), Grażyna Biała (Author)
• Format: Book
• Published: MDPI AG, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Two polyphenols-hyperoside (HYP) and protocatechuic acid (PCA) were reported to exert antidepressant activity in rodents after acute treatment. Our previous study also showed that this activity might have been influenced by the monoaminergic system and the upregulation of the brain-derived neurotrop...