The impact of extended adjuvant temozolomide in newly diagnosed glioblastoma multiforme: a meta-analysis and systematic review

• Autores principales: Ehsan Alimohammadi (Autor), Seyed Reza Bagheri (Autor), Shahram Taheri (Autor), Maliheh Dayani (Autor), Alireza Abdi (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2020-02-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Surgical resection followed by concurrent radiation therapy and temozolomide (TMZ) chemotherapy is the current standard treatment for glioblastoma multiforme (GBM). The present metaanalysis investigated the impact of prolonged TMZ maintenance therapy (more than 6 cycles) in comparison with standard...