Fibroblast Growth Factor Type 2 (FGF2) Administration Attenuated the Clinical Manifestations of Preeclampsia in a Murine Model Induced by L-NAME

• Main Authors: Margarita L Martinez-Fierro (Author), Gloria Patricia Hernadez-Delgadillo (Author), Jose Feliciano Flores-Mendoza (Author), Claudia Daniela Alvarez-Zuñiga (Author), Martha Lizeth Diaz-Lozano (Author), Ivan Delgado-Enciso (Author), Viktor Javier Romero-Diaz (Author), Adrian Lopez-Saucedo (Author), Iram Pablo Rodriguez-Sanchez (Author), Ivan Alberto Marino-Martinez (Author), Idalia Garza-Veloz (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: In preeclampsia, a hypertensive disorder of pregnancy, the poor remodeling of spiral arteries leads to placental hypoperfusion and ischemia, provoking generalized maternal endothelial dysfunction and, in severe cases, death. Endothelial and placental remodeling is important for correct p...