Effect of the C3a-Receptor Antagonist SB 290157 on Anti-OVA Polyclonal Antibody-Induced Arthritis

• Main Authors: Pilaiwanwadee Hutamekalin (Author), Kohei Takeda (Author), Mitsuhiro Tani (Author), Yuko Tsuga (Author), Naoki Ogawa (Author), Nobuaki Mizutani (Author), Shin Yoshino (Author)
• Format: Book
• Published: Elsevier, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

It was investigated whether the C3a-receptor antagonist (C3aRA) SB 290157 was involved in the suppression of anti-OVA pAb-induced arthritis because it is well known that anaphylatoxin C3a plays a crucial role in the development of an effective inflammatory response during complement activation. Anti...