Attenuation of Cigarette-Smoke-Induced Oxidative Stress, Senescence, and Inflammation by Berberine-Loaded Liquid Crystalline Nanoparticles: In Vitro Study in 16HBE and RAW264.7 Cells

• Main Authors: Keshav Raj Paudel (Author), Nisha Panth (Author), Bikash Manandhar (Author), Sachin Kumar Singh (Author), Gaurav Gupta (Author), Peter R. Wich (Author), Srinivas Nammi (Author), Ronan MacLoughlin (Author), Jon Adams (Author), Majid Ebrahimi Warkiani (Author), Dinesh Kumar Chellappan (Author), Brian G. Oliver (Author), Philip M. Hansbro (Author), Kamal Dua (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cigarette smoke is considered a primary risk factor for chronic obstructive pulmonary disease. Numerous toxicants present in cigarette smoke are known to induce oxidative stress and airway inflammation that further exacerbate disease progression. Generally, the broncho-epithelial cells and alveolar...