Melatonin prevents bone destruction in mice with retinoic acid-induced osteoporosis

• Main Authors: Xudong Wang (Author), Tongzhou Liang (Author), Yuanxin Zhu (Author), Jincheng Qiu (Author), Xianjian Qiu (Author), Chengjie Lian (Author), Bo Gao (Author), Yan Peng (Author), Anjing Liang (Author), Hang Zhou (Author), Xiaoming Yang (Author), Zhiheng Liao (Author), Yongyong Li (Author), Caixia Xu (Author), Peiqiang Su (Author), Dongsheng Huang (Author)
• Format: Book
• Published: BMC, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The protective effect of melatonin against bone metabolism imbalance in osteoporosis (OP) induced by drugs such as retinoic acid (RA) is unclear. The aim of this study was to explore the role of melatonin in bone destruction based on a mouse model. Methods RA-induced OP model mic...