cAMP driven UCP1 induction in human adipocytes requires ATGL-catalyzed lipolysis

• Główni autorzy: Anand Desai (Autor), Zinger Yang Loureiro (Autor), Tiffany DeSouza (Autor), Qin Yang (Autor), Javier Solivan-Rivera (Autor), Silvia Corvera (Autor)
• Format: Książka
• Wydane: Elsevier, 2024-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Objective: The uncoupling protein 1 (UCP1) is induced in brown or "beige" adipocytes through catecholamine-induced cAMP signaling, which activates diverse transcription factors. UCP1 expression can also be enhanced by PPARγ agonists such as rosiglitazone (Rsg). However, it is unclear wheth...