Angiostatin Inhibition of Vascular Endothelial Growth Factor- Stimulated Nitric Oxide Production in Endothelial Cells

• Hauptverfasser: Satoru Takahashi (Verfasst von), Tomohiro Shinya (Verfasst von), Akinori Sugiyama (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2010-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Angiostatin (AS), a proteolytic fragment of plasminogen, is a potent antiangiogenic factor. It was reported that AS attenuates the vasodilatory response to vascular endothelial growth factor (VEGF) in isolated interventricular arterioles. Here, we investigated the effect of AS on nitric oxide (NO) p...