EGFR exon 20 insertion mutations in advanced non-small-cell lung cancer: current status and perspectives

• Main Authors: Jiabao Hou (Author), Hongle Li (Author), Shuxiang Ma (Author), Zhen He (Author), Sen Yang (Author), Lidan Hao (Author), Hanqiong Zhou (Author), Zhe Zhang (Author), Jing Han (Author), Li Wang (Author), Qiming Wang (Author)
• Format: Book
• Published: BMC, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Platinum-based chemotherapy was previously the first-choice treatment for lung cancer. The discovery of epidermal growth factor receptor (EGFR) gene mutations and the development of EGFR tyrosine kinase inhibitors (TKIs) marked the beginning of the targeted therapy era for non-small-cell lu...