Development and In Vitro-Ex Vivo Evaluation of Novel Polymeric Nasal Donepezil Films for Potential Use in Alzheimer's Disease Using Experimental Design

The objective and novelty of the present study is the development and optimization of innovative nasal film of Donepezil hydrochloride (DH) for potential use in Alzheimer's disease. Hydroxypropyl-methyl-cellulose E50 (factor A) nasal films, with Polyethylene glycol 400 as plasticizer (factor B)...

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Autors principals: Paraskevi Papakyriakopoulou (Autor), Dimitrios M. Rekkas (Autor), Gaia Colombo (Autor), Georgia Valsami (Autor)
Format: Llibre
Publicat: MDPI AG, 2022-08-01T00:00:00Z.
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