Bazedoxifene Plays a Protective Role against Inflammatory Injury of Endothelial Cells by Targeting CD40

• Main Authors: Wenmin Song (Author), Yu Lv (Author), Zizhao Tang (Author), Fangqin Nie (Author), Panhao Huang (Author), Qi Pei (Author), Ren Guo (Author)
• Format: Book
• Published: Hindawi-Wiley, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The inflammatory response and oxidative stress play key roles in the formation and development of atherosclerosis. Bazedoxifene is a new IL6/GP130 inhibitor recommended by the FDA for clinical use as a selective estrogen receptor modulator. However, its role in cardiovascular diseases has been poorl...