Intradermal immunization with botulinum neurotoxin serotype E DNA vaccine induces humoral and cellular immunity and protects against lethal toxin challenge

• Main Authors: Na Young Kim (Author), Hye Bin Ahn (Author), Chi Ho Yu (Author), Dong Hyun Song (Author), Gyeung Haeng Hur (Author), Young Kee Shin (Author), Sungho Shin (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Botulinum neurotoxins (BoNTs) produced by the spore-forming, gram-positive, anaerobic bacterium Clostridium botulinum are the most toxic substances known and cause botulism, flaccid paralysis, or death. Owing to their high lethality, BoNTs are classified as category A agents by the Centers for Disea...