Clinical Assessment of Breast Cancer Resistance Protein (BCRP)-Mediated Drug-Drug Interactions of Sepiapterin with Curcumin and Rosuvastatin in Healthy Volunteers

• প্রধান লেখক: Lan Gao (লেখক), Diksha Kaushik (লেখক), Kimberly Ingalls (লেখক), Sarah Milner (লেখক), Neil Smith (লেখক), Ronald Kong (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Adis, Springer Healthcare, 2024-09-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Background and Objective Sepiapterin, also known as PTC923 and CNSA-001, is a synthetic form of endogenous sepiapterin being developed as a novel oral treatment for phenylketonuria. Sepiapterin is a natural precursor of tetrahydrobiopterin (BH4) and, when orally administered, is converted t...