Pharmacological and Biological Study of Microencapsulated Probucol-Secondary Bile Acid in a Diseased Mouse Model

• Main Authors: Susbin Raj Wagle (Author), Bozica Kovacevic (Author), Corina Mihaela Ionescu (Author), Daniel Walker (Author), Melissa Jones (Author), Louise Carey (Author), Ryusuke Takechi (Author), Momir Mikov (Author), Armin Mooranian (Author), Hani Al-Salami (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Probucol (PB) is a highly lipophilic drug with potential protective effects on pancreatic β-cells from inflammation and oxidation. PB has poor bioavailability and solubility, and despite many attempts, significant improvement in antidiabetic effects or absorption has yet to be discovered. Recently,...