Clinical pharmacokinetics of methotrexate in the treatment of acute lymphoblastic leukemia and non-Hodgkin lymphoma in pediatric patients

High dose methotrexate (MTX) is used in therapy of acute lymphoblastic leukemia and non-Hodgkin lymphoma in pediatric patients. It acts as competitive inhibitor of dihydrofolate reductase and consequently inhibits synthesis of deoxyribonucleic acid. The bioavailability is dependent upon dose and rou...

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Bibliographic Details
Main Authors: Škorić Biljana (Author), Jovanović Marija (Author), Miljković Branislava (Author), Kuzmanović Miloš (Author), Vučićević Katarina (Author)
Format: Book
Published: Pharmaceutical Association of Serbia, Belgrade, Serbia, 2020-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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