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Clinical pharmacokinetics of methotrexate in the treatment of acute lymphoblastic leukemia and non-Hodgkin lymphoma in pediatric patients

High dose methotrexate (MTX) is used in therapy of acute lymphoblastic leukemia and non-Hodgkin lymphoma in pediatric patients. It acts as competitive inhibitor of dihydrofolate reductase and consequently inhibits synthesis of deoxyribonucleic acid. The bioavailability is dependent upon dose and rou...

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主要な著者:	Škorić Biljana (著者), Jovanović Marija (著者), Miljković Branislava (著者), Kuzmanović Miloš (著者), Vučićević Katarina (著者)
フォーマット:	図書
出版事項:	Pharmaceutical Association of Serbia, Belgrade, Serbia, 2020-01-01T00:00:00Z.
主題:	article
オンライン･アクセス:	Connect to this object online.
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