FORMULATION AND OPTIMIZATION OF PIOGLITAZONE SOLID DISPERSIONS PREPARED BY HOT MELT EXTRUSION TECHNIQUE

• Váldodahkkit: Vidyadhara Suryadevara (Dahkki), Ashis Kumar Mehatha (Dahkki), Sasidhar R Lankapalli (Dahkki), Abhijit M Deshmukh (Dahkki), Laxmana P Sambath (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Universitas Gadjah Mada, 2013-07-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The main objective of the present study was to develop a novel and stable pioglitazone loaded solid dispersions with enhanced solubility and dissolution rate. Different drug-to-carrier ratios were prepared by employing hot melt extrusion technique. These formulations were characterized for solid sta...