Olopatadine Suppresses the Migration of THP-1 Monocytes Induced by S100A12 Protein

• Main Authors: Kazuya Kishimoto (Author), Satoshi Kaneko (Author), Kenji Ohmori (Author), Tadafumi Tamura (Author), Kazuhide Hasegawa (Author)
• Format: Book
• Published: Hindawi Limited, 2006-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Olopatadine hydrochloride (olopatadine) is an antiallergic drug with histamine H1 receptor antagonistic activity. Recently, olopatadine has been shown to bind to S100A12 which is a member of the S100 family of calcium-binding proteins, and exerts multiple proinflammatory activities including chemota...