The potential of ribonucleotide reductase M2 as a novel prognostic maker and therapeutic target to inhibit medulloblastoma proliferation, migration, and invasiveness

• Main Authors: Xuanxuan Wu (Author), Pan Gou (Author), Chencheng Fang (Author), Yudong Zhou (Author), Lusheng Li (Author), Xuan Zhai (Author), Ping Liang (Author)
• Format: Book
• Published: Wiley, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The crucial role of ribonucleotide reductase M2 (RRM2) enzyme in cancer occurrence and progression has been well‐established, but its specific function and significance in medulloblastoma (MB) remains largely unknown. First, we conducted a bioinformatics analysis of public genomic databases...