Adaptation of the intact proviral DNA assay to a nanowell-based digital PCR platform

• मुख्य लेखकों: Carolin Tumpach (लेखक), Catherine R. Cochrane (लेखक), Youry Kim (लेखक), Jesslyn Ong (लेखक), Ajantha Rhodes (लेखक), Thomas A. Angelovich (लेखक), Melissa J. Churchill (लेखक), Sharon R. Lewin (लेखक), Sushama Telwatte (लेखक), Michael Roche (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2023-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Quantification of intact proviruses is a critical measurement in HIV cure studies both in vitro and in vivo. The widely adopted 'intact proviral DNA assay' (IPDA), designed to discriminate and quantify genetically intact HIV proviruses based on detection of two HIV sequence-specific target...