Stimulation of Hepatic Ferritinophagy Mitigates <i>Irp2</i> Depletion-Induced Anemia

• প্রধান লেখক: Yutong Liu (লেখক), Yuxuan Li (লেখক), Liu Yang (লেখক), Jiaqi Shen (লেখক), Hongting Zhao (লেখক), Weichen Dong (লেখক), Yanzhong Chang (লেখক), Tong Qiao (লেখক), Kuanyu Li (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2023-02-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Background: Iron regulatory proteins (IRPs) maintain cellular iron homeostasis. Due to aberrant tissue-iron distribution, <i>Irp2</i>-deficient mice suffer microcytic anemia and neurodegeneration, while iron overload occurs in the liver and intestine. We previously found that <i>Ir...