Genotype-phenotype correlations in patients with breast cancer and BRCA1 mutations (4153delA, 185delAG, 5382insC)
Hereditary breast cancer (BC) associated with BRCA1 mutations is characterized by a number of features as compared to sporadic and BRCA2- associated BC. Structural and functional changes in mutant proteins in accordance with the type and locus of BRCA1 mutations determine different variants of a BC...
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2014-07-01T00:00:00Z.
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