Pharmacokinetics of caffeine self-administered in overdose in a Japanese patient admitted to hospital

• Main Authors: Koichiro Adachi (Author), Satoru Beppu (Author), Mariko Terashima (Author), Toshiaki Fukuda (Author), Jun Tomizawa (Author), Makiko Shimizu (Author), Hiroshi Yamazaki (Author)
• Format: Book
• Published: BMC, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Caffeine (0.1 g) is used as a central nervous system stimulant and as a nontoxic phenotyping probe for cytochrome P450 1A2. However, an increasing number of suicide attempts by caffeine overdose have been recently reported. Case presentation A 25-year-old woman (body weight, 43 k...