Human Telomerase Reverse Transcriptase (hTERT) Expression in Patients with Chronic Myelogenous Leukemia at Different Phases of the Disease

• Main Authors: K Alimoghadam (Author), N Eynolahi (Author), Y Mortazavi (Author), Sh Rostami (Author), SH Ghaffari (Author), A Amini (Author), Y Gahani (Author), A Ghavamzadeh (Author)
• Format: Book
• Published: Tehran University of Medical Sciences, 2008-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Aim: Chronic Myelogenous Leukemia (CML) is a clonal hematopoietic stem cell disorder characterized by a translocation between chromosome 9 and 22 called Philadelphia Chromosome. Telomerase- essential enzyme that adds telomeric repeats into the telomeres- maintains integrity of chromos...