Stability-indicating assay method for determination of actarit, its process related impurities and degradation products: Insight into stability profile and degradation pathwaysâ

• Egile Nagusiak: A. Abiramasundari (Egilea), Rahul P. Joshi (Egilea), Hitesh B. Jalani (Egilea), Jayesh A. Sharma (Egilea), Dhaivat H. Pandya (Egilea), Amit N. Pandya (Egilea), Vasudevan Sudarsanam (Egilea), Kamala K. Vasu (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2014-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The stability of the drug actarit was studied under different stress conditions like hydrolysis (acid, alkaline and neutral), oxidation, photolysis and thermal degradation as recommended by International Conference on Harmonization (ICH) guidelines. Drug was found to be unstable in acidic, basic and...