Differences in type I interferon signaling antagonism by dengue viruses in human and non-human primate cell lines.

• Asıl Yazarlar: Freddy A Medina (Yazar), Giselle Torres-Malavé (Yazar), Amanda J Chase (Yazar), Gilberto A Santiago (Yazar), Juan F Medina (Yazar), Luis M Santiago (Yazar), Jorge L Muñoz-Jordán (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Public Library of Science (PLoS), 2015-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

BACKGROUND/OBJECTIVES:In vitro studies have shown that dengue virus (DENV) can thwart the actions of interferon (IFN)-α/β and prevent the development of an antiviral state in infected cells. Clinical studies looking at gene expression in patients with severe dengue show a reduced expression of inter...