Estimation of the Difference in Colistin Plasma Levels in Critically Ill Patients with Favorable or Unfavorable Clinical Outcomes

• Main Authors: Jose Sanabria (Author), Vivian Garzón (Author), Tatiana Pacheco (Author), Maria-Paula Avila (Author), Julio-Cesar Garcia (Author), Diego Jaimes (Author), Angela Torres (Author), Rosa-Helena Bustos (Author), Javier Escobar-Perez (Author), Deisy Abril (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In recent decades, antimicrobial resistance (AMR) has led to an increased use of therapeutic alternatives. Among these options, colistin continues to be an option for the treatment of multi-resistant (MDR) Gram-negative bacterial infections. However, due to its high toxicity (nephrotoxicity and neur...