An Olive-Derived Extract 20% Rich in Hydroxytyrosol Prevents β-Amyloid Aggregation and Oxidative Stress, Two Features of Alzheimer Disease, via SKN-1/NRF2 and HSP-16.2 in <i>Caenorhabditis elegans</i>

• Main Authors: Jose M. Romero-Márquez (Author), María D. Navarro-Hortal (Author), Victoria Jiménez-Trigo (Author), Pedro Muñoz-Ollero (Author), Tamara Y. Forbes-Hernández (Author), Adelaida Esteban-Muñoz (Author), Francesca Giampieri (Author), Irene Delgado Noya (Author), Pedro Bullón (Author), Laura Vera-Ramírez (Author), Maurizio Battino (Author), Cristina Sánchez-González (Author), José L. Quiles (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Olive milling produces olive oil and different by-products, all of them very rich in different bioactive compounds like the phenolic alcohol hydroxytyrosol. The aim of the present study was to investigate the effects of an olive fruit extract 20% rich in hydroxytyrosol on the molecular mechanisms as...