Toll-like receptor 4 inhibitor protects against retinal ganglion cell damage induced by optic nerve crush in mice

Toll-like receptor 4 inhibitor protects against retinal ganglion cell damage induced by optic nerve crush in mice

Toll-like receptor 4 (TLR4) plays key roles in innate immune responses and inflammatory reactions. TAK-242 (resatorvid) is a small-molecule cyclohexene derivative that selectively inhibits TLR4 signaling pathways and suppresses inflammatory reactions. Here we investigated the protective effects of T...

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Main Authors: Yukimichi Nakano (Author), Masamitsu Shimazawa (Author), Kazuki Ojino (Author), Hiroshi Izawa (Author), Hiroto Takeuchi (Author), Yuki Inoue (Author), Kazuhiro Tsuruma (Author), Hideaki Hara (Author)
Format: Book
Published: Elsevier, 2017-03-01T00:00:00Z.
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