Cocrystals Enhance Biopharmaceutical and Antimicrobial Properties of Norfloxacin

• Main Authors: Samantha Nascimento Gomes (Author), Isabela Fanelli Barreto Biscaia (Author), Diana Schon Lopes (Author), Mariana Mengarda (Author), Fábio Seigi Murakami (Author), Paulo Renato Oliveira (Author), Larissa Sakis Bernardi (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A solvate cocrystal of the antimicrobial norfloxacin (NFX) was formed by using isonicotinamide (INA) as a coformer with the solvent evaporation technique. The cocrystal formation was confirmed by performing solid-state characterization techniques. We evaluated the dissolution under supersaturated co...