Sperm-associated antigen 6 (Spag6) mutation leads to vestibular dysfunction in mice

Sperm-associated antigen 6 (Spag6) mutation leads to vestibular dysfunction in mice

Spag6 encodes an axoneme central apparatus protein that is required for normal flagellar and cilia motility. Recent findings suggest that Spag6 plays a role in hearing and planar cell polarity (PCP) in the cochlea of the inner ear. However, a role for Spag6 in the vestibule has not yet been explored...

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Main Authors: Xiaofei Li (Author), Daogong Zhang (Author), Lei Xu (Author), Wenwen Liu (Author), Na Zhang (Author), Jerome F. Strauss, III (Author), Zhibing Zhang (Author), Haibo Wang (Author)
Format: Book
Published: Elsevier, 2021-12-01T00:00:00Z.
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